Bram Lambrus

Academic Titles: 
BCMB Graduate Student
NSF Graduate Research Fellow
Appointments/Affiliations: 

BS, University Of Illinois at Urbana Champaign, IL

Selected Publications:
A new mode of mitotic surveillance. Lambrus, B.G. and Holland, A.J.*, Trends in Cell Biology 8924(17): 30014-4 (2017). [ link ] [ pdf ]
A USP28-53BP1-p53-p21 signaling axis arrests growth following centrosome loss or prolonged mitosis. Lambrus, B.G., Daggubati, V., Uetake, Y., Scott, P.M., Clutario, K.M., Sluder, G., Holland, A.J. Journal of Cell Biology 214:143-153. (2016). Preview     Nature Reviews Highlight [ link ] [ pdf ]
p53 protects against genome instability following centriole duplication failure. Lambrus, B.G., Uetake, Y., Clutario K.M., Daggubati, V., Snyder, M., Sluder, G., Holland, A.J. Journal of Cell Biology 210(1), 63-77. (2015). Science Daily     Hopkins News Release     Genetic Engineering and Biotechnology News [ link ] [ pdf ]
STIL binding to Plk4 activates kinase activity to promote centriole duplication. Moyer T.C., Clutario K.M., Lambrus B.G., Daggubati V., Holland A.J. Journal of Cell Biology 209(6), 863-78. (2015). JCB podcast [ link ] [ pdf ]