Tyler Moyer

Academic Titles: 
BCMB Graduate Student
NSF Graduate Research Fellow
Appointments/Affiliations: 

BS, Bucknell University, PA

Current: Voyager Therapeutics

Selected Publications:
PLK4 promotes centriole duplication by phosphorylating STIL to link the procentriole to the microtubule wall. Moyer, T.C. and Holland, A.J. eLIFE 8: e46054. (2019). Biomedical Picture of the Day  [ link ] [ pdf ]
Applying the auxin-inducible degradation system for rapid protein depletion in mammalian cells. Lambrus, B.G., Moyer, T.C., and Holland, A.J. Methods in Cell Biol 358(6364): 716-8. (2017). [ link ] [ pdf ]
CDK1 Prevents Unscheduled PLK4-STIL Complex Assembly in Centriole Biogenesis. Zitouni, S., Francia, M.E., Leal, F., Montenegro Gouveia, S., Nabais, C., Duarte, P., Gilberto, S., Brito, D., Moyer, T., Kandels-Lewis, S., Ohta, M., Kitagawa, D., Holland, A.J., Karsenti, E., Lorca, T., Lince-Faria, M., Bettencourt-Dias, M. Current Biology 26(9):1127-37. (2016). [ link ] [ pdf ]
Generation of a conditional analog-sensitive kinase in human cells using CRISPR/Cas9-mediated genome engineering. Moyer T.C., Holland A.J. Methods in Cell Biol 129:19-36. (2015). [ link ] [ pdf ]
STIL binding to Plk4 activates kinase activity to promote centriole duplication. Moyer T.C., Clutario K.M., Lambrus B.G., Daggubati V., Holland A.J. Journal of Cell Biology 209(6), 863-78. (2015). JCB podcast   [ link ] [ pdf ]